For that reason, children and women who are pregnant or breastfeeding should not take niacin supplements in excess of the dri unless it's recommended by a doctor. People with uncontrolled gout should also not take niacin supplements. Webmd medical Reference reviewed by carmen Patrick mohan on June 12, 2017 sources sources: Fundukian,.,. The gale Encyclopedia of Alternative medicine, third edition, 2009. Natural Medicines Comprehensive database: niacin. Natural Standard Patient Monograph, niacin. Endotext Internet: "Triglyceride lowering Drugs: niacin january 2017.
Vitamin B3 - niacin » Hälsosidorna
It can cause liver problems, stomach ulcers, changes to veins glucose levels, muscle damage, low blood pressure, heart rhythm changes, and other issues. People with any health condition including liver or kidney disease, diabetes, high blood pressure, or cardiovascular problems need to talk to a doctor before using niacin supplements. Do not treat high cholesterol on your own with over-the-counter niacin supplements. If you take any medicines or supplements regularly, talk to your doctor before you start using niacin supplements. They could interact with medicines like diabetes drugs, blood thinners, anticonvulsants, blood pressure medicines, thyroid hormones, and antibiotics as well as supplements like ginkgo biloba and some antioxidants. Alcohol might increase the risk of liver problems. Though niacin is often used along with statins for high cholesterol, this combination may increase the risk for side effects. Get advice from your health care provider. At the low dri doses, niacin is safe for everyone. However, at the higher amounts used to treat medical conditions, it can have risks.
Improves skin Function niacin helps protect skin cells from sun damage, whether it's used orally or applied to the skin in lotions prenatal ( 19 ). And recent research suggests it may help prevent some types of skin cancer ( 20 ). A 2015 study found that taking 500 mg of nicotinamide (a form of niacin ) twice daily reduced rates of non-melanoma skin cancer among people at a high risk of skin cancer ( 20 ). May reduce symptoms of Arthritis One preliminary study showed that niacin helped ease some of the symptoms of osteoarthritis, improving joint mobility and reducing the need for nsaids ( 21 ). Another study in lab rats found that an injection with the vitamin reduced inflammation related to arthritis ( 22 ). Although this is promising, more research is needed in this area. Treats Pellagra severe niacin deficiency causes a condition called pellagra ( 4, 23 ). Thus, taking a niacin supplement is the main treatment for pellagra.
Niacin occurs naturally in many foods, including greens, meat, poultry, fish, and eggs, although in a fraction of the dose shown to achieve changes in cholesterol. Many products are also fortified with niacin during manufacturing. What are the risks of taking niacin? Niacin can cause flushing, especially when you first begin taking. Your health care provider will probably suggest increasing oral the dose slowly to reduce this problem. He or she might also offer a time-release prescription formulation to control flushing. Niacin can cause upset stomach and diarrhea. However, all of these side effects tend to fade over time. Niacin does have risks.
On one hand, it can help lower the high cholesterol levels that are often seen in people with type 2 diabetes ( 14 ). On the other hand, it has the potential to increase blood sugar levels. As a result, people with diabetes who take niacin to treat high cholesterol levels also need to monitor their blood sugar levels carefully ( 14 ). Boosts Brain Function your brain needs niacin, as a part of the coenzymes nad and nadp, to get energy and function properly. In fact, brain fog and even psychiatric symptoms have been associated with niacin deficiency ( 15 ). Some types of schizophrenia can be treated with niacin, as it helps undo the damage to brain cells that occurs as a result of deficiency ( 16 ). And preliminary research shows that it could also help keep the brain healthy in cases of Alzheimer's disease. However, results have been mixed ( 17, 18 ).
Niacin (Vitamin B3) : Benefits, dosage, sources, risks
Consequently, this lowers the production of low-density lipoprotein (LDL) and very low-density lipoprotein (vldl). Therapeutic doses are needed to achieve these effects on cholesterol and triglyceride levels ( 1 ). May help Prevent heart Disease niacin 's effect on cholesterol is one way it can help prevent heart disease. But newer dames research also suggests another mechanism by which it benefits your heart. It can help reduce oxidative stress and inflammation, both of which are involved in atherosclerosis, the hardening of the arteries ( 1 ). Some research has suggested niacin therapy, either alone or in combination with statins, could help lower the risk of health problems related to heart disease ( 12 ).
However, the research is mixed. A recent review concluded that niacin therapy doesn't significantly help reduce the risk of heart attack, stroke or death from heart disease among people with heart disease or those who are at a high risk ( 10 ). May help Treat Type 1 diabetes Type 1 diabetes is an autoimmune disease in which the body attacks and destroys insulin-creating per cells in the pancreas. There's research to suggest that niacin could help protect those cells and possibly even lower the risk of type 1 diabetes in at-risk children ( 2, 13 ). However, for people with type 2 diabetes, the role of niacin is more complicated.
Severe niacin deficiency, or pellagra, mostly occurs in third world countries, where diets are not varied. Bottom Line: niacin is a vitamin that makes up two major cofactors, which are compounds that help enzymes work. How much niacin you need is based on the dietary reference Intake and depends on your age and gender ( 4, 5 ). Therapeutic doses of niacin are higher than the recommended amounts and should only be taken under medical supervision. Here are the recommended dietary allowances (RDAs) for niacin ( 4 infants 06 months: 2 mg/day* 712 months: 4 mg/day* *Adequate Intake (AI) Children 13 years: 6 mg/day 48 years: 8 mg/day 913 years: 12 mg/day adolescents and Adults boys and men, 14 years and. Men need 16 mg per day, while most women need 14 mg per day.
Lowers ldl cholesterol niacin has been used since the 1950s to treat high cholesterol ( 6 ). In fact, it can lower levels of "bad" ldl cholesterol by 520 ( 7, 8 ). However, niacin is not the primary treatment for high cholesterol due to its possible side effects ( 9 ). Rather, it's primarily used as a cholesterol-lowering treatment for people who can't tolerate statins ( 10 ). Increases hdl cholesterol In addition to lowering ldl cholesterol, niacin also raises "good" hdl cholesterol. It does this by helping to stop the breakdown of apolipoprotein A1, a protein that helps make hdl ( 11 ). Studies have shown that niacin raises hdl cholesterol levels by 1535 ( 7 ). Lowers Triglycerides niacin 's third benefit for blood fats is that it can lower triglycerides by 2050 ( 7 ). It does this by stopping the action of an enzyme that's involved in triglyceride synthesis ( 1 ).
Vitamin B3 - wikipedia
Your body gets niacin through food, but also makes it from the amino acid tryptophan. Bottom Line: niacin is one of eight water-soluble b vitamins. It's also known as nicotinic acid, niacinamide and nicotinamide. As with all of the b vitamins, niacin helps convert food into energy by helping enzymes do their job. Specifically, niacin is a major component of nad and nadp, two coenzymes that are involved in cellular metabolism. Furthermore, it plays bikes a role in cell signaling and making and repairing dna, in addition to acting as an antioxidant ( 3 ). Niacin, deficiency, you can get a sense of what a nutrient does by looking at what happens when voor you're deficient. These are some of the symptoms of niacin deficiency: Memory loss and mental confusion, fatigue. Depression, headache, diarrhea, skin problems, that being said, deficiency is very rare in most Western countries.
Niacin is one of the eight b-vitamins, and it's also called vitamin,. There are two main chemical forms and each has different effects on the body. Both forms are found in foods as well as supplements. Nicotinic acid: As a supplement, nicotinic acid is the form of niacin that's symptoms used to treat high cholesterol and heart disease ( 1 ). Niacinamide or nicotinamide: Unlike nicotinic acid, niacinamide doesn't lower cholesterol. However, it can help treat type 1 diabetes, some skin conditions and schizophrenia ( 2 ). Niacin is water-soluble, so your body doesn't store. This also means that your body can excrete excess amounts of the vitamin if it's not needed.
dosage for you. Everyone needs a certain amount of niacin - from food or supplements - for the body to function normally. This amount is called the dietary reference intake (dri a term that is replacing the older and more familiar rda (recommended daily allowance). For niacin, the dris vary with age and other factors: Children: between 2-16 milligrams daily, depending on age men: 16 milligrams daily women: 14 milligrams daily women ( pregnant 18 milligrams daily women ( breastfeeding 17 milligrams daily maximum daily intake for adults of all. If your doctor prescribes niacin, you might want to take it with food. . This can prevent upset stomach. . To reduce flushing - a harmless but uncomfortable side effect of niacin that describes redness and warmth in the face and neck - your health care provider might recommend taking niacin along with aspirin, an nsaid painkiller, or an antihistamine until tolerance to the niacin. Can you get niacin naturally from foods?
However, niacin is only effective as a cholesterol treatment at fairly high doses. These doses could pose risks, such as liver damage, gastrointestinal problems, or glucose intolerance. So don't treat yourself with over-the-counter niacin supplements. Instead, get advice from your health care provider, who can prescribe fda-approved doses of niacin instead. Niacin has other benefits. There's wat good evidence that it helps reduce atherosclerosis, or hardening of the arteries in some people. For people who have already had a heart attack, niacin seems to lower the risk of a second one.
Top 10 Vitamin B3 niacin foods
Having enough niacin, or vitamin B3, in the body is important for general good health. As a treatment, higher phlebotomist amounts of niacin can improve cholesterol levels and lower cardiovascular risks. Why do people take niacin? As a cholesterol treatment, there are good studies showing that niacin can boost levels of good. Hdl cholesterol and lower triglycerides. Niacin also modestly lowers bad. It's often prescribed in combination with statins for cholesterol control, such as, crestor, lescol, or, lipitor.